is a waste produced during the body breaks down substances called purines
. Purines are found in many foods and drinks, such as liver, anchovies, mackerel, dried beans and peas, beer, and wine.Most uric acid dissolves in blood and travels to the kidneys, where it passes out in urine. If your body produces too much uric acid or doesn't remove enough of it, you can get sick.
Normal values fall between 3.0 to 7.0 mg/dL.
High levels of uric acid in the body is called hyperuricemia. It is an excessive concentration of uric acid in the blood. Some people develop gout, kidney stones or kidney failure due to high uric acid levels. A high uric acid level may appear prior to the development of high blood pressure, heart disease or chronic kidney disease. But it's often unclear whether a high uric acid level is a direct cause or merely an early warning sign of these conditions.
Higher-than-normal level of uric acid may be due to:
- Acidosis
- Alcoholism
- Diabetes
- Gout
- Hypoparathyroidism
- Lead poisoning
- Leukemia
- Nephrolithiasis
- Polycythemia vera
- Renal failure
- Toxemia of pregnancy
- Purine-rich diet
- Excessive exercise
- Chemotherapy-related side effects
- Fanconi syndrome
- Wilson's disease
- Syndrome of inappropriate antidiuretic hormone (SIADH) secretion
- Low purine diet
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